Cardiobacterium hominis is a slow-growing, fastidious, capnophilic, Gram- negative bacillus represented by the “C” in HACEK, an acronym for. Cardiobacterium hominis is a member of the HACEK group (Haemophilus paraphrophilus, Haemophilus parainfluenzae, Aggregatibacter. Cardiobacterium hominis, a microaerophilic, pleomorphic gram-negative bacillus , is one of the AACEK organisms. C. hominis is a component of the normal flora.

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It does not demonstrate urease, catalase, nitrate reductase, phenylalanine deaminase, beta galactosidase, lysine decarboxylase, ornithine decarboxylase or arginine dihydrolase activity 1 We describe a case of culture-negative endocarditis in which a modified Steiner stain revealed bacterial structures in the resected heart valve material. A total of 61 English-language cases were identified from 48 manuscripts [ 13 – 49 ]. Jolie A, Gnann JW.

However, pulmonary valve involvement has been documented The size of the vegetations, as determined by echocardiography, was cardlobacterium in only four cases: Antibacterial efficacy of ciprofloxacin in a case of endocarditis due to Cardiobacterium hominis.

Case Presentation A fifty-six-year-old Caucasian man with no significant past medical history was transferred to the tertiary care Health Sciences Centre Winnipeg, Manitoba from a peripheral hospital with new-onset congestive heart failure. Information on symptoms and putative risk factors was available for 58 patients and 61 patients, respectively Table 1. Infective endocarditis due to Eikenella cardjobacterium Congestive heart failure is seen more often with C.


On chest x-ray, bilateral perihilar infiltrates, worse on the right side, were observed, consistent with asymmetric alveolar edema and possible pneumonia.

Despite, or perhaps in keeping with its chronicity, C. No vertebral biopsies were done. Cardiobacterium hominis in yominis specimens. Cardiobacterium hominis is a member of the normal upper respiratory flora in humans and may be found rarely on other mucosal surfaces. Diagnosis requires identification of the pathogen from blood or vegetation by either culture or molecular techniques.

Characteristics that help distinguish C. Their patient developed renal toxicity while receiving treatment with mezlocillin and gentamicin, relapsed on mezlocillin alone, cardiobacteriuk was cured with ciprofloxacin.

Most cases have been in middle-aged adults and, in contrast to endocarditis due to other HACEK organisms, the aortic valve is most frequently involved 6. Snyder A, Ellner PD. Am J Hematol ; Among at uominis 13 reported cases of endocarditis that have occurred with gastrointestinal endoscopythree non- Cardiobacterium cases occurred caddiobacterium colonoscopy [ 63 – 66 ].

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Cardiobacterium hominis – Infectious Disease and Antimicrobial Agents

Jolie A, Gnann JW. Table 8 displays biochemical properties that help differentiate C. Infect Dis Rep ;5: Roth spots have been rarely reported Abdominal abscess due to Cardiobacterium hominis and Clostridium bifermentans. In this case, the patient was treated successfully with ciprofloxacin 3.


At that time, antibiotic treatment was changed to cefotaxime. Urinalysis showed an erythrocyte count of 10—25 cells per high-power field and a leukocyte count of 3—5 cells per high-power field; urine culture yielded 50,—, Escherichia coli. Two holes were observed in the aortic valve noted to be quadricuspidwhich was also replaced. Ten days after admission, Cardiobacterium hominis was identified as the pathogen. Rickettsia felis Flea-borne spotted fever.

Influence of referral bias on the apparent clinical spectrum of infective endocarditis. Recently, two isolates with beta-lactamase production have been reported [ 2426 ].

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Detton E, Glikmanas M. He suffered a ruptured cerebral aneurysm, underwent aortic valve replacement, and was treated successfully with parenteral antibiotics and surgery. Therapy was almost always given by the intravenous route. Thirteen non-English-language cases from 12 manuscripts were not included.

Dental work is a potential cause of bacteremia and has been cited as a risk factor leading to infection. Boll Ist Sieroter Milan. The present patient had a quadricuspid aortic valve, and this may have placed him at risk for this infection.