The methanol leaf extract of Mallotus oppositifolius was evaluated for anti- inflammatory activity in rats and mice using acute and chronic anti-inflammatory. Mallotus oppositifolius is widely distributed and occurs from Senegal east to Ethiopia and south to Angola and Mozambique, and also in Madagascar. Biochem Res Int. ; doi: // Epub Oct Evaluation of Mallotus oppositifolius Methanol Leaf Extract on the.

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The crushed or chewed fresh leaves, sometimes mixed with butter, are put on cuts oopositifolius sores as a haemostatic and antibacterial, and on skin eruptions and rashes for fast healing.

The mixtures were filtered with Whatman number 1 filter paper.

Flora of Zimbabwe: Species information: Mallotus oppositifolius var. oppositifolius

Therefore we selected and evaluated the methanol leaf extract of MP for its claimed antidiabetic potentials considering also, its effect on total cholesterol and biomarkers of oxidative stress in vivo and in vitrorespectively.

Leaf sap is used as nose drops or eye drops and the head is massaged with the pulped leaves to treat headache.

They are also applied nallotus burns to calm pain. The authors declare that there is no conflict of interests as per this work, the project was not funded by any organization, and appropriate acknowledgments have been given to those deserving. A root decoction and leaf sap are taken to treat pneumonia, vomiting and chest pain.

Antibacterial properties of Mallotus oppositifolius and Dissotis rotundifolia. Mallotus o;positifolius is commonly browsed by cattle. B 10 x – 29k – jpg ww2.

Although antibacterial and anti-inflammatory activities have been demonstrated in in-vitro tests, more research is needed to evaluate its potential as a medicinal plant.


The leaves contain a higher concentration of these compounds than the roots. Reactive oxygen species ROS have been implicated in many pathologies such as heart diseases, cancers, arteriosclerosis, diabetes mellitus, and arthritis [ 22 ]. The extract was not toxic. Mallotus oppositifolius fruiting branch obtained from Runetwork.

BoxAH Wageningen, Netherlands. The effect of MP extract on the fasting blood glucose levels of maklotus rats. Journal of Veterinary Medicine, Series A, 47 9: View at Google Scholar G. Ethical guidelines in animal handling and use were strictly adhered to in the oppositiffolius of the study. Bioactive components of the leaf extracts of M. B 10 x – 33k – jpg ww2. Only few species occur in tropical Africa: Click on “show more” to view them.

It is deep-rooting and has a root: Antioxidant and anti-inflammatory activities of Mallotus oppositifolius in model systems. Journal of Applied Entomology 7: There are also lipoprotein abnormalities with diabetes mellitus [ 5 ].

The leaves have ingredients of common antidysentery, antimalarial, and anti-inflammatory remedies [ 8 ]. A steam bath with the leaves is taken to treat headache, epilepsy or mental illness. Small germplasm collections are maintained in the United Kingdom and South Africa.

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Alkaloids of plant origin such as Solanine from S. Mallotus oppositifolius leaves and stem bark have several interesting local medicinal uses, including analgesic, antibacterial, anthelminthic mallotuss haemostatic uses. With on-going researches in diabetes and oral hypoglycaemic agents OHAthe management of DM is still a global problem.

The variations in the cholesterol values of amllotus rats compared with the control groups were not significant. The crushed leaves or leaf sap are applied to aching teeth and inflamed eyes.

It has an extensive system of fine roots, indicating its potential for use in agroforestry and land management. In West Africa it is grown in and around cassava fields to reduce the impact of animals that feed on the leaves, as they prefer Mallotus oppositifolius leaves.

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Mallotus oppositifolius is widely distributed and occurs from Senegal east to Maolotus and south to Angola and Mozambique, and also in Madagascar. The findings with MP extract in this study confirm its folkloric uses oppositifoilus the management of diabetes, thus making Mallotus oppositifolius a probable plant for drug discoveries.

Diabetes which is associated with impaired glucose metabolism leads to oxidative stress which with an attendant protein glycation will produce free radicals [ 19 ]. Alloxan, from the literature, has been shown to cause hyperglycaemia in laboratory animals due to increased oxidative stress by elaborated free radicals [ 12 ], thus a model for type 1 diabetes studies.

Different leaf, root and stem bark extracts showed significant antibacterial activity against Staphylococcus aureusEscherichia coliPseudomonas aeruginosa and Bacillus subtilis oppositifoljus vitro. The total antioxidant activity of the Mallotus oppositifolius MP extract was estimated by the ferric opposihifolius antioxidant power FRAP assay [ 16 ] and the 1,1-diphenylpicryl-hydrazyl DPPH photometric assay [ 17 ].

Aqueous and ethanol extracts of dried leaves oppositkfolius significant antifungal activity in vitro against Aspergillus flavusCandida albicansMicrosporum audouiniiPenicillium sp. The procedures were carried out in triplicates and the mean used in computations. It has a high growth rate compared to other commonly used browse plants.