Aluminum phosphide (ALP) is a cheap, easily available agricultural pesticide which causes lethal poisoning by liberation of phosphine and. Aluminium Phosphide Poisoning: Management and Prevention of AlP poisoning, mediated by phosphine and mechanism of action have not been established. Aluminium phosphide (AlP) is a cheap solid fumigant and a highly toxic pesticide that is commonly used for grain preservation. AlP has currently generated.

Author: Sanos Akinonos
Country: Mayotte
Language: English (Spanish)
Genre: Music
Published (Last): 5 March 2012
Pages: 481
PDF File Size: 5.97 Mb
ePub File Size: 2.89 Mb
ISBN: 968-5-34104-920-4
Downloads: 33983
Price: Free* [*Free Regsitration Required]
Uploader: Mera

In an era when there is an unscientific insistence on speciality specific research by regulatory bodies in medical education, JCDR supports collaborative research across specialities. Pesticides Aluminium phosphide Organophosphates.

Managing aluminum phosphide poisonings. IV fluids, Hemacel and RL were started. Aluminium phosphide poisoning — A review. Phosphine- induced oxidative damage in rats: Reversible myocardial injury associated with aluminium phosphide poisoning. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR”.

J Emerg Trauma Shock ;4: AlP has currently generated interest with increasing number of cases in the past four decades because of its increased use for agricultural and nonagricultural purposes, and also its easy availability in the markets has led to its increased misuse to commit suicide.

V was repeated every hour for three consecutive hours and then 8th hourly and Inj hydrocortisone mg iv 6th hourly and Inj Calcium Gluconate 1 amp iv 6th hourly were given for the first 48 hours. The mechanism of toxicity includes cellular hypoxia due to the effect on mitochondria, inhibition of cytochrome C oxidase and formation of highly reactive hydroxyl radicals. Acute aluminium phosphide poisoning, what is new?. The effect of phosphine on electron transport of mitochondria. Intra-aortic balloon pump in toxic myocarditis due to aluminium phosphide poisoning.


How to cite this URL: Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help.

We have been asked clarifications on several occasions and have been happy to provide them and it exemplifies the commitment to quality of the team at JCDR.

Key Message The favourable outcome of Celphos poisoning correlates best with the prompt removal of poison from the body and good supportive treatment.

I appreciate the Editor, Dr.

Open in a separate window. Its wide based indexing and open access publications attracts many authors as well as readers For authors, the manuscripts can be uploaded online through an easily navigable portal, on other hand, reviewers appreciate the systematic handling ppoisoning all manuscripts.

This article aims to identify the salient features and mechanism of AlP poisoning along with its management strategies and prognostic variables. Dexamethasone 8 mg and IV fluids. Views Read Edit View history. As hydrogen sulfide also changes the color, its presence could be differentiate by using lead acetate paper, i.

Aluminium phosphide poisoning – Wikipedia

Annals of Saudi Medicine. It ‘s a multispecialty journal, publishing high quality articles.

Care of patients with severe poisoning can be enhanced by consultation with a medical toxicologist or a regional poison center. Successful management of aluminium phosphide poisoning using intravenous lipid emulsion: Evaluation of histopathological changes in fatal aluminium phosphide poisoning. Intravascular haemolysis after aluminium phosphide ingestion. The salt is usually available in tablet and pellet forms.


The effect of phosphine on electron transport in mitochondria. Adrenocortical involvement in aluminium phosphide poisoning. J Am Med Assoc. Celphos is formulated as a greenish gray tablet of 3 g, which in the presence of moisture or HCl, releases phosphine:.

Severe myocardial depression in a patient with aluminium phosphide poisoning: Authors are the souls of any journal, and deserve much respect.

Managing aluminum phosphide poisonings

As each poison has a definite elimination time, so also is the case with AlP. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb of its first issue, it contained 5 articles only, and now in its recent volume published in Aprilit contained 67 manuscripts.

This is important to attain adequate tissue perfusion and oxygenation and physiologic metabolic milieu compatible with life until the tissue poison levels are reduced and spontaneous circulation is restored.

Br J Pharmacol ; In mild poisoning pkisoning, repeated vomiting, diarrhea, headache, abdominal discomfort or pain and tachycardia are common clinical features, and these patients usually show recovery.

Abstract Aluminum phosphide AlP is a cheap, effective and commonly used pesticide. Phosphorus Pesticides Aluminium phosphide Organophosphates. Clin Toxicol Phila ;