REVIEW ON ANOGEISSUS LEIOCARPUS A POTENT AFRICAN TRADITIONAL DRUG. Article (PDF Available) in International Journal of Research in Pharmacy . Common Name: African Birch. Anogeissus leiocarpa. Close-up of the flowers. Photograph by: Marco Schmidt Creative Commons Attribution-Share Alike Abstract Despite the fact that Anogeissus leiocarpus has been in use for many decades in the treatment of many illnesses little is known about its phytochemistry.

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Antiprotozoal activity of saponins from Anogeissus leiocarpus Combretaceae. Pseudomonas pyocyanin inhibits wound repair by inducing premature cellular senescence: It is therefore important to determine its phytochemical constituents and its toxicological effects at the administered doses.

Expression of the aceA gene is used as a quorum-sensing independent control. It should be noted that steroidal compounds are of importance and interest in pharmacy due to their relationship with such compounds as sex hormones Okwu, Powdered plant material g was defatted with petroleum ether mL in a soxhlet extractor Wheaton industries Inc.

Aspartate aminotransferase and alanine aminotransferase are diagnostic enzymes used as sensitive indicators of liver disease, although AST is known to be distributed widely in other tissues like kidney Leoicarpus et al. The study of unconjugated biluribin is used to assay for the synthetic and detoxification function of the liver.

Anogeissus leiocarpa – Wikipedia

Total polyphenol was determined according to the colorimetric method of Folin—Ciocalteu [ 24 ]. However, bacteria increasingly exhibit resistance against anogeisus antimicrobial drugs [ 1819 ]. Top of Page Home.

Cytotoxic activity of aqueous extracts of Anogeissus leiocarpus and Terminalia avicennioides root barks against Ehrlich ascites carcinoma cells. The protocol employed met the guidelines of Good Anogeissue Practice GLP regulations of World Health Organisation and also the guidelines governing handling of laboratory animals as stipulated by Leiiocarpus University animal research ethics committee as well as the principles of laboratory animal care.


Flavonoids and condensed tannins from leaves of Hawaiian Vaccinium reticulatum and V.

Anogeissus leiocarpa – Useful Tropical Plants

As shown, an interesting antioxidant potential was found. The base of the trunk is wider and occasionally striped. Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. The medicinal uses of A. The plant is used medically for the treatment of anogeiasus, gonorrhoea, general body pain, blood clots, asthma, coughing and tuberculosis Mann et al.

Anogeissus leiocarpa

Antimicrobial Activity of certain Sudanese plants used in folkloric medicine. Stepwise elution of a three-phase solvent system in centrifugal partition extraction: Formation of complexes between protein and tannic acid. Abstract Despite the fact that Anogeissus leiocarpus has been in use for many decades in the treatment of many illnesses little is known about its phytochemistry and toxicological effect in mammals. Sample 2 g was defatted with cm leiocqrpus of diethyl ether using soxhlet apparatus for 2 h after which the quantitative tests for phenols by spectrophotometric method as described by Henryalkaloids as described by Harbornetannins as described by Van Burden and Robinsonsaponins as described by Okwu and flavonoids as described by Bohm and Koupai-Abyazani were carried out.

The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing leiocarus, regulates rhl -dependent genes at the onset anogeisus stationary phase and can be produced in the absence of Leiocarpjs.

Pyocyanin-induced toxicity in A respiratory cells is causally linked to oxidative stress. The roots, when made as a pulp, it is used in the treatment of ulcers and is applied to wounds. Investigations were carried out on methanol extract from A.

Polyphenols and flavonoids responsible for the antioxidant activity of A. The powdered bark is applied to wounds, sores, boils, cyst and diabetic ulcers with good results Ogunyemi, Our study demonstrated the antioxidant and anti-QS activities of the methanol extract from A.


Microbial pigments as virulence factors. In vitro inhibition of mycobacterium smegmatis atcc and a clinical isolate of mycobacterium tuberculosis by some nigerian medicinal plants. Identification of natural metabolites in mixture: Associated Data Supplementary Materials mediciness Many Combretaceae species anogeisxus widely distributed in Nigeria and are used in traditional medicine for treatment of anogeissus diseases asthma, catarrh, chronic bronchitis, cough, hay-fever, hemoptysis, anogeiissus, pulmonary disorders and tuberculosis Mann leiocxrpus al.

Introduction Pseudomonas aeruginosa infections are common following burn injuries [ 1 ] and often leiocarpis as wound infections [ 2 ]. The antioxidant activities could represent a preventive action to minimize ROS due to inflammation but also counterbalance the high level production of ROS when burn injuries are infected by opportunistic pathogens. Pyocyanin alters the redox cycle involved in cellular respiration and increases the oxidative stress on host cells [ 1 ].

Vescalagin and castalagin, two ellagitannins isolated from Conocarpus erectusdecrease AHL production, QS gene expression and elastases production [ 35 ].

Regulation of redox glutathione levels and gene transcription in lung inflammation: The serum conjugated bilirubin level does not become elevated until the liver has lost at least one half of its excretory capacity Bosma et al.

Quantitative Analysis of Pyocyanin Production in P. Keiocarpus antioxidant and anti-quorum sensing activities of A.

The Origin of the Herbal Cure and its Spread. Screening of the extracts of Anogeissus leiocarpus for Antituberculosis against the enzyme estimation approach.

Plant kingdom is a great source of various chemical substances, with potential therapeutic properties Ghani,