Isolation, Characterization and Evaluation of Anti-convulsant Activity of Rubus Antidiabetic Activity of the Plant Abutilon indicum in Streptozotocin Induced. Abutilon hirtum extract and fractions exhibited anti-inflammatory analgesic, antipyretic and antipyretic activities which may be attributed by the. Abutilon indicum Sweet is an Asia phytomedicine traditionally used to treat several disorders, including diabetes mellitus. However, molecular.

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Enter your contact information below to receive full paper. Traditionally the plant parts are used as sour, astringent and diuretic and is useful in conditions such vata, tumours, fever, neuralgia and splenopathy. As shown in Figure 6the cells treated with the extract increased relative luciferase unit RLU in a dose-response manner.

View at Google Scholar N.

Evidence-Based Complementary and Alternative Medicine

As there is no detailed on the standardisation work reported on stem, the physicochemical parameters, brief study on pharmacological activities and microbial contamination analysis are carried out. We have reported that the phytochemical ativity of the whole plant extract revealed the presence of alkaloids, flavonoids, and tannins [ 11 ].

Extracts of abutiloon roxburgii were tested for growth inhibitory against bacterial plant pathogens, mosquito. The alkaloid berberine has also been reported to activate GLUT1-mediated glucose uptake [ 48 ]. This study demonstrates that the milk decoction of AR is potent as compared to aqueous decoction of AR.

II, Amarin, Bangkok, Thailand, View at Google Scholar S. Most plants with antidiabetic properties have been found to contain metabolites such as glycosides, alkaloids and flavonoids [ 9 ].


Indeed, seven compounds were isolated from A.

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Antidiabetic Activity of A. The results revealed that the leaves contain steroids, sapogenins, carbohydrates and flavonoids. Pinus roxburgii sarg is one of the species belonging to family pinaceae found in East Asia-Himalayas from Afghanistan to Bhutan, forms extensive forests to meters and does best on north slopes on good soils.

Dhirender Kaushik, Ajay Kumar, A. Similarly petroleum ether extract and benzene extract were found to possess very good analgesic property.

Anti-diabetic and analgesic activity of leaves of abutilon indicum

The turpine obtained from resin of tree is antiseptic, diaphoretic, diuretic, rubefacient, stimulant and vermifuge. Incredible Gift in the Lap of Himalayas. In traditional systems of activiy, different parts leaves, stem, flower, root, seeds and even whole plant of tinospora cardifolia Menispermaceaecommonly known as Guduchi are antidiabtic. As shown in Figure 1administration of A. Thus, extrapancreatic action such as stimulating liver and muscle fructose-2,6-bisphosphate formation may be involved in the effect of both glibenclamide and extracts used in this study rather than insulin secretion.

Present investigation includes examination of morphological and microscopic characters, ash value, extractive values and Phytochemical evaluations including qualitative chemical examination of active constituents were carried out. The thorax was opened, and the diaphragm was removed. Originally, TZDs were identified based on their antihyperglycemic activity, but they are also able to improve other abnormalities associated with type 2 diabetes, such as hyperlipidemia, atherosclerosis, hypertension, chronic inflammation and fibrinolytic state.


Hypoadiponectinemia appears to play an important causal role in insulin resistance, type 2 DM and metabolic syndrome [ 4041 ]. Crude extract of A. We found that A.

Clayton, Medical Plants in Thailandvol. The distribution region plays an important determinant of pine distribution and abundance in the landscape. The aim of this study was to evaluate whether extract of A.

Assays were performed in triplicate for each experiment group as previously described [ 24 ]. The leaves of Abutilon indicum Activitu. Pharmacognostical Studies of the Leaves of Cayratia carnosa Gagnep. With respect to its traditional use, A. Subsequently, we examined the effect of the extract on transcription activation of GLUT1.

Indexed in Science Citation Index Expanded. Abstract Abutilon indicum L. This result will require confirmation such as measuring extracellular signal regulated kinases ERKswhich have been known to be responsible for the expression of GLUT1 [ 48 ].

The medicinal plants are widely used by the traditional medical practitioners for curing various diseases in their day to day practice.

Volume2,Issue2 – Pharmacognosy Phytochemistry

Table of Contents Alerts. The animals were weighed on day 0, 4, 7, 11 and 14 for corrected doses of medication. The resulting water fraction was freeze-dried, followed by generating brown powder